An Efficient Approach Towards Synthesis of Pyrimidine Derivatives Bearing Pyridine Nucleus Using L-Proline as a Catalyst

Authors

  • Nirul V. Gothi  Arts, Science & R. A. Patel commerce college, Bhadran, Gujarat, India

Keywords:

Pyrimidine, Pyridine, Biginelli reaction, biological activities, NMR, L-proline

Abstract

Pyridine and pyrimidine containing compounds found to possess various biological activities. Biginelli reaction is one of the finest approaches to synthesize pyrimidine derivatives that offer diverse choice of substitutions. This paper describes an efficient approach towards synthesis of pyrimidine derivatives bearing pyridine nucleus using L-proline as a catalyst. Twenty compounds were synthesized in high purity using a simple synthetic program. All the compounds were characterized by NMR, IR and mass spectroscopy.

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International Journal of Scientific Research in Science and Technology

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Published

2017-02-28

Issue

Volume 3, Issue 1, January-February-2017

Section

Research Articles

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How to Cite

[1]
Nirul V. Gothi, " An Efficient Approach Towards Synthesis of Pyrimidine Derivatives Bearing Pyridine Nucleus Using L-Proline as a Catalyst, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 3, Issue 1, pp.674-681, January-February-2017.